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Qsymia online Rated 1.00 out of 5 based on 1 customer rating ( 1 customer review) $ 180.00 – $ 780.00 Usual Adult Dose of Qsymia for Weight Loss: -Initial dose: Take one capsule of the lowest dose (phentermine 3.75 mg/topiramate 23 mg extended-release) orally once a day in the morning for the first 14 days.