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Buy Arimidex Online Firstly,Common side effects include hot flashes, altered mood, joint pain, and nausea.Secondly, Severe side effects include an increase risk of heart disease and osteoporosis. Arimidex is in the aromatase-inhibiting family of medications. It works by blocking the creation of estrogen. Arimidex was patented in 1987 and approved for medical use in 1995.