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The effects of a psychedelic substance will be influenced by the dosage, individual physiology, set (your mindset), and setting (your environment). A microdose is typically considered to be about 1/10th to 1/20th of a full dose, and for psilocybin mushrooms, this is generally in the range of 0.1g to 0.3g (100mg to 300mg) for many people.