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In the 1980s, MDMA spread into
nightlife and rave culture and was subsequently banned. By 2014, MDMA
was estimated to be one of the most popular recreational drugs used in
the world, alongside cocaine and cannabis. Researchers are investigating
whether MDMA may assist in treatment-resistant posttraumatic stress
disorder (PTSD), social anxiety in autistic adults, and anxiety in those
with life-threatening illness.