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Anadenanthera peregrina, aka YOPO seeds have an array of naturally occurring psychedelic substances of the tryptamine class, of structural relatives to 5-HO-DMT Bufotenin, NN-DMT and, 5-MeO-DMT have been used as entheogens by South American shamans for thousands of years, and have recently been demonstrated to induce mystical experiences, and is distributed in a wide variety of plant species, as well as in the venom of a single psychoactive toad species Bufo Alvaris.